To expand on Scott's answer. The JDBBASE APIs that Scott is referring to give you a LOT more tools at your disposal (as opposed to ER only) to construct some very complex SQL that you simply cannot do in ER code alone.
However, to strictly answer your question, when you do ER code F0101.Select, F0101.Update F0101.Insert, etc. or use data bound controls in a form (like a grid tied to a business view) you are "execute SQL update/delete/select from enterprise one application", so you may want to be a little more specific on what you are trying to accomplish.