There should not be any set up issues. There is a few differences in functionality, a new way to process interims is one of them, but nothing earth shattering from a learning curve standpoint. Depending on where you are in your testing/CRP is the area I would be most concerned about. As an application consultant myself, I would have to evaluate how this might affect my project plan. You should do a full integrated CRP test on ERP8.0 at a minimum.
Not to get off topic,but have you applied the baseline ESU for payroll for your XE environment? IF not you cannot run the most current version of vertex and any additional SARs from JDE might require the baseline,
Scott Warwick
Anderson Warwick Consulting Services Inc.