A client of mine had Double Take set up as their Disaster Recovery solution. They were on ERP 8, SQL Server 2000, and Citrix as their remote client. They had Double Take performing replication on the SQL database, and other files that changed during the course of package builds, etc.
They had their Production data and System database replicated, along with the JDE objects on the Production Enterprise Server and Deployment Server. The DV and PY data and objects were on a different server, and were not part of the DR as it was considered non-crucial.